During Carnival, Venice is a city of anonymity. When six friends decide to take advantage of that, the result is murder.

Tom, a middle-aged American expatriate living in Paris, suggests to his circle of friends that they play a game. Each will travel to Venice, and , disguised as his or her “true self,” meet near the Campanile in the Piazza San Marco. The winner will be the one who correctly identifies the most of the other five. But before the game can start, Brian, dressed Medusa, is found floating dead in a canal. Reality suddenly becomes a moot point when no one is who he or she appears to be, when stripping away one disguise only reveals another. Before Carnival is over, the remaining five friends will find their lives irrevocably entangled--if they can stay alive.