Benton McCaleb and his band of bold-spirited cowboys brave over a thousand treacherous miles to drive 2400 head of ornery cattle into Wyoming's Sweetwater Valley. They're setting up a ranch just north of Cheyenne when a ruthless railroad baron and his hired killers try to force them off the land.

With the help of a Shoshoni Indian tribe and Buffalo Bill Cody, McCaleb and his men vow to stand and fight. Outgunned and outmanned, they'll wage the most ferocious battle of their lives - to win the right to call the land their own.