Kafka's Curse is the story of Oscar Kahn (born Omar Khan), a "colored" Muslim architect passing as a Jewish man, married to a white woman, who eventually experiences a mysterious physical transformation, the likes of which no one can explain. As his brother Malik, a politician firmly rooted in Islam, tries to come to terms with his brother's betrayal, he abandons both his principles and his family when he falls in love with Amina, Omar's beautiful psychotherapist.