The planet has been overwhelmed. A new and unknown disease of unparalleled destructive force has sprung up almost simultaneously in every corner of civilization, outrunning all attempts at quarantine, all but destrying the human race. One survivor, strangely immune to the effects of the epidemic, ventures forward to experience a world without man. What he, who will ultimately become the last American, will discover will be far more -- and far more astonishing -- than anything he'd either dreaded or hoped for.